Frontier Biodefense Fellowship

Spend 15 weeks in London doing high-impact biodefense projects with expert mentorship.

Know someone who'd be great? Recommend and receive $1,000 if we accept them.

Dates:
Next dates to be announced
Location:
London, LISA
Stipend:
£15,000–£18,000

Why do we run this fellowship?

Biodefense talent is bottlenecked. The field needs more serious researchers, entrepreneurs, policymakers, executors working on frontier threats — including PPE, biohardening, detection, and adjacent areas. The fellowship exists to grow that group.

What you get during the fellowship

  • Expert mentorship

    Weekly 1-on-1s with established experts providing methodological expertise, critical feedback, and strategic direction.

  • Management

    Pivotal's dedicated project and research managers help you scope projects, stay on track, navigate blockers, and plan your career.

  • LISA workspace

    In-person co-working at the London Initiative for Safe AI. Lunch and dinner included weekdays.

  • Financial support

    Stipend plus travel to London, housing support for non-London fellows, and the resources you need for your research to succeed.

  • Workshops and speakers

    Q&A sessions with leading domain experts and hands-on workshops to sharpen your thinking and expand your network.

  • Extensions

    Up to 2 months of continued financial support, mentorship, management, and workspace for strong projects.

Areas we're excited about

Fellows work on projects defined by their mentors. We're particularly excited to support projects on:

  • PPE

    Next-generation personal protective equipment for catastrophic biological threats.

  • Transmission suppression

    "Biohardening" — interventions that reduce transmission at population scale.

  • Detection

    Early-warning systems and pathogen-agnostic surveillance approaches.

…plus adjacent areas of biosecurity. Fellows produce research papers, policy reports, blog series, open-source tools, documented repos, and similar outputs.

What previous fellows have worked on

All projects
  • Ongoing
  • Biodefense

Assessing biological tool capabilities for hazardous virus design

This project assesses the capabilities of AI-enabled and non-AI biological tools relevant to hazardous-virus design and examines their implications for biosecurity risk.

Mentor:
Sana Zakaria
  • Ongoing
  • Biodefense

Automating recombination risk assessment: a quantitative surprise score for emerging viral variants

This project automates viral threat detection by screening viral genomes for high-risk recombination events. It applies a sliding-window algorithm across sequence junctions in NCBI and CASPER metagenomic data, producing a quantitative “surprise score” that automatically flags novel, anomalous viral variants for early biosurveillance triage.

Fellow:
Rhea Agarwal
  • Ongoing
  • Biodefense

Biohardening for extreme biological threats

This project revises and expands Coefficient Giving’s practical guide to household protection during extreme biological events, covering methods for reducing exposure through air, food, water, surfaces and other pathways. It assesses existing recommendations, identifies evidence gaps and develops clearer guidance for maintaining protection throughout prolonged emergencies.

Mentor:
Aman Patel
  • Ongoing
  • Biodefense

Can we make enough? Global peptide manufacturing capacity under biothreat

This project, conducted with Sebastian Oehm and Askar Kleefeldt at SynX Therapeutics, maps global macrocyclic-peptide manufacturing capacity and its supply-chain vulnerabilities. It tests whether rapid-response therapeutics could be produced at population scale during a severe pandemic or deliberate attack, including threats enabled by AI-driven biological design.

  • Ongoing
  • Biodefense

Designing a research decision-tree for drug-free nasal sprays

This project ranks candidate experiments by cost, timeline and decision-relevance, and establishes the funding decision rules to pre-commit to before results arrive.

  • Ongoing
  • Biodefense

Detecting novel viruses in wastewater data using genome language models

This project assesses whether genome language models can identify viruses that are increasingly different from those in their training data, informing both detection efforts and assessments of the models’ own capabilities.

Fellow:
Noga Aharony

Application Process

You apply to work with one or more mentors. Shortlisted candidates move on to the video interview, a work task and a personal interview.

  1. Written application

    You, your interests, mentor preferences. · 1–2h

  2. Video interview

    Short recorded interview.

  3. Work task

    Mentor-specific research exercise.

  4. Personal interview

    With the team or your mentors.

FAQ

Who is eligible to apply?

Primarily PhD students and early-career professionals, plus outstanding undergrads. Backgrounds we've seen across our fellowships include biology, public health, ML, policy, and physics. Your background matters less than motivation and ability.

Should I apply?

If you're reading this, probably yes. The fellowship is selective, but that alone shouldn't put you off. If your interests and background seem like a plausible fit, applying is often worth it.

Can I bring my own project?

You need to apply to at least one mentor. That said, there's often room to shape the project together with the guidance of your mentor.

What does the application involve?

A written application (~1–2 hours), then for shortlisted candidates: a short video interview, a mentor-specific work task, and a personal interview.

Can I participate remotely?

Fellows are in-person at LISA in London. We make rare exceptions for people with a strong independent research track record. If you can't fully be in-person, apply either way and flag it in the form.

Can I participate part-time?

The fellowship is full-time. Small side commitments are usually fine and you can mention them in your application.

Can fellows work in teams?

Some mentors have fellows work in teams, others work one-on-one. Either way, collaboration between fellows is common and encouraged.

What outputs are expected?

Research papers, policy reports, blog series, open-source tools, documented repos, and similar formats — depending on what suits the project. You retain ownership over your research.

Will I be employed by Pivotal? Do I need a UK visa?

No, Pivotal will not employ you, but we'll have a stipend agreement. Meeting entry requirements is your responsibility — we have an info doc on entry requirements and can sometimes help with the process.

What about housing and travel?

We cover travel to and from London. If you don't already live here, you'll receive housing support on top of the stipend.

Why is Pivotal running a biosecurity fellowship?

The field needs more good researchers working on frontier biological threats. The Frontier Biodefense Fellowship is our first dedicated biosecurity programme, alongside our existing AI safety fellowship.

Can I work with Pivotal in other ways?

Yes, have a look at Get involved on our About page, or just get in touch.